Dr. Daniel Von Hoff, MD

ENDECE™ LLC Scientific Advisory Board Member

Daniel D. Von Hoff, MD, is a Clinical Professor of Medicine at the University of Arizona. He is Senior Investigator and Director of Translational Drug Development (TD2) for Phoenix-based Translational Genomics Research Institute (TGen) and head of its Pancreatic Cancer Research Program. He is also Chief Scientific Officer for US Oncology.

Dr. Von Hoff’s major interest is in the development of new anticancer agents, both in the clinic and in the laboratory. He and his colleagues were involved in the development of many agents we now routinely use, including: mitoxantrone, fludarabine, paclitaxel, docetaxel, gemcitabine, CPT-11, and others. At present, he and his colleagues are concentrating on the development of molecularly targeted therapies.

Dr. Von Hoff’s laboratory interests and contributions have been in the area of in vitro drug sensitivity testing to individualize treatment for the patient. He and his laboratory are now concentrating on discovery of new targets in pancreatic cancer. Dr. Von Hoff has published more than 515 papers, 129 book chapters, and more than 861 abstracts.

Dr. Von Hoff was appointed to President Bush’s National Cancer Advisory Board in June 2004 to serve through March 2010. Dr. Von Hoff is the past President of the American Association for Cancer Research, a Fellow of the American College of Physicians, and a member and past board member of the American Society of Clinical Oncology. He is a founder of ILEX Oncology, Inc., acquired by Genzyme. He is founder and Editor Emeritus of Investigational New Drugs; The Journal of New Anticancer Agents; and, Editor-in-Chief of Molecular Cancer Therapeutics. He is also proud to have been a mentor and teacher for multiple medical students, medical oncology fellows, graduate students, and post-doctoral fellows.